You need to know the first basic steps of making a layout, for me, i started with a LAYOUT MAKER, start with a simple generator:
and play around with the codes like changing the colors, search google for more tweaks and codes and just be creative, sooner or later, you’ll get used to it, and it will be one of the easiest things for you to do :]
Myspace Flash Layouts and all Div Design Layouts
make your own myspace layout using this easy to use myspace profile editor: